New dissolving film strips for weight management
When it comes to oral dissolving thin films for prescriptions, Riize Health has led the way with innovations for men’s and women’s sexual health, and for weight loss. Riize oral film strips use the latest in thin film manufacturing technology, and are made domestically, under strict guidelines. Through the Riize Health telemedicine platform, patients can get a free personalized assessment, with prescriptions from licensed medical professionals. Because of this, Riize Health is leading the way in the use of dissolving film strips for oral drug delivery.
Riize Health has now introduced another innovation for weight loss and management – Riize Weight Management Strips – a perfect product for your GLP-1 weight loss program. When placed under the tongue (sublingually), the strips quickly dissolve, delivering a micro-dose of semaglutide directly to the bloodstream. It allows you to get all the benefits of semaglutide (same ingredient as Ozempic®) without having to give yourself injections.
What makes Riize Weight Management strips so effective?
The development of dissolving drug film strips grew out of the effectiveness that certain drugs had when administered either sublingually or buccally (between the cheek and gum). They were invented as a way to deliver prescription drugs to pediatric and geriatric patients, and those with medically diagnosed swallowing issures. However, it was personal care products, not prescription drugs, that first brought them to mainstream awareness. The first well-known dissolving oral film strips were for a breath freshener developed by Pfizer and marketed as Listerine® pocket packs™, and for Chloraseptic®, the topical sore throat treatment.
The tissues inside the mouth, referred to as the mucosa, have a thin membrane structure, and thus a high permeability – in some cases, up to 4,000 times more permeable than the skin. This thin membrane structure also has a profuse and dense capillary system, giving substances immediate access to the general bloodstream. This results in quick and effective bioavailability. By entering systemic circulation directly via the oral tissue, the drug being administered retains more potency by avoiding degradation in the gastrointestinal tract and the first pass effects of normal metabolic processes.
Riize Weight Management Strips are designed around these well-established physical delivery mechanisms for the direct application and effectiveness of semaglutide micro-dosing. The strips also incorporate the latest state-of-the-art oral film strip technology, which has continued to improve the dosing, reliability and speed of drug delivery to the system. Riize has taken advantage of all those improvements in the design and production of Riize Weight Management Strips.
Oral dissolving films are composed of single or multiple polymer-based layers. The dose of the active pharmaceutical ingredient (API) is controlled by the size and thickness of the film. New techniques have been developed to deal with solubility differences in the APIs being used, including nanoparticle technology to reduce particle size. The overall result in manufacturing advances is a consistent, accurate and effective dosage, that is highly soluble. Continuing advancements in oral dissolving film strips are in response to a rapidly growing market, which has increased by approximately 80% in the last ten years.
The appeal of oral dissolving strips
When it comes to ways to take a prescription, oral dissolving film strips are hard to resist. After all, what better way to take a medicine, than to simply put something light under your tongue and have it melt away in seconds? In the case of a semaglutide prescription, it’s clearly easier and more appealing than giving yourself an injection. It’s easy to see why dissolvable oral film strips have become not only widely accepted, but preferred whenever they are available as an option.
What are the advantages of oral dissolving strips?
The most obvious advantages of oral film strips are ease-of-use and convenience. They dissolve rapidly and disperse their active ingredient when placed in the mouth, without the need for water. In every day medications, this helps to avoid any swallowing difficulties a patient might have. With Riize Weight Management Strips, the advantage is in not needing an injection.
Another advantage is highly accurate and consistent dosing. Most other forms of oral drugs, namely pills and capsules, contain as much as 60% excipients – usually non-therapeutic “junk” that has been added for stability or bulk. With oral dissolving film strips, there is neither the room nor the need for additives beyond the active pharmaceutical ingredient (API). Other oral formats, such as gummies or lozenges, can also contain excipients, but are more likely to contain sugar.
But perhaps the most significant advantage of oral film drug delivery is in their bioavailability. Being absorbed directly in the mouth limits exposure to the gastrointestinal tract and the effects of what’s known as first-pass metabolism. This is when the drug is first metabolized through the digestive tract, which degrades it and results in a reduced concentration of the active ingredients being delivered. The first-pass effect is often associated with the ingredient being metabolized in the liver, but it can also happen in other body tissues, such as in the lungs and vascular system. Studies of some drugs have shown that only about 4% of the API was reaching the system after going through first-pass metabolism.
Staying consistently, fully-hydrated is not only good for overall health, but also promotes weight loss. In addition to being a natural appetite suppressant, speeding up metabolism, eliminating waste, maintaining muscle tone and increasing the rate of using fat cells for energy, water is at the foundation of any successful diet and weight management program. Whereas diet changes require some thought and effort, drinking the proper amount of water every day is one of the easiest things you can do.
All of these advantages are making dissolving oral film strips a growing, preferred choice for the administration of traditional drugs, biologics, supplements and possibly even vaccines. The use of oral dissolving film strips is growing as a viable means of administration and delivery of both active pharmaceutical ingredients (APIs) and active non-pharmaceutical ingredients (ANPIs). In addition to over-the-counter medications and non-pharma supplements, such as nutraceuticals, oral dissolving strips are even being used for veterinary and pet supplement applications.
An easy way to maintain your weight loss
Riize Health’s track record of delivering effective, innovative personal care products in oral film strip form continues with Riize Weight Management Strips. They are packaged for portable, easy handling and use, and to insure maximum stability. And getting the prescription is just as easy. Riize Health has eliminated the need for in-person doctor visit through a state-of-the-art, secure telemedicine platform. You still will need to go through an assessment process, to ensure you are medically qualified for the prescription, as Riize places your health and well-being as our top priority. Once you are cleared for your prescription, you can make, or continue a semaglutide program as part of a successful weight loss journey.
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